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OpenVax

Open source software for personalized cancer vaccines

  • Overview
  • Contributors
  • Publications
  • Clinical Trials
  • Software
  • Blog

  • The OpenVax group develops open source software for designing personalized cancer vaccines. Our work includes a bioinformatics pipeline for selecting a peptide vaccine from DNA and RNA sequencing of a patient's tumor, as well as a collection of Python libraries developed to support it (see our GitHub page). We have helped initiate and run several clinical trials of personalized cancer vaccines at the Mount Sinai Hospital, in collaboration with Dr. Nina Bhardwaj, Dr. Adilia Hormigo, Dr. Matthew Galsky, and Mount Sinai's Vaccine and Cell Therapy Lab.

  • Blog

    Thoughts and research snippets

    OpenVax Neoantigen Prediction Pipeline: A Tutorial
    October 21, 2020
    We've previously written about the OpenVax neoantigen prediction pipeline, which is the...
    Computational Pipeline for Neoantigen Vaccine Trials at Mount Sinai
    August 3, 2018
    Cancer immunotherapy aims to recruit the body's own immune system to attack a tumor, which...
    GLIPH & TCR clustering
    June 27, 2018 · immunology
    Uri Laserson organized a delightful class at Mount Sinai called Applications of DNA Sequencing...
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