OpenVax
Open source software for personalized cancer vaccines
The OpenVax group develops open source software for designing personalized cancer vaccines. Our work includes a bioinformatics pipeline for selecting a peptide vaccine from DNA and RNA sequencing of a patient's tumor, as well as a collection of Python libraries developed to support it (see our GitHub page). We have helped initiate and run several clinical trials of personalized cancer vaccines at the Mount Sinai Hospital, in collaboration with Dr. Nina Bhardwaj, Dr. Adilia Hormigo, Dr. Matthew Galsky, and Mount Sinai's Vaccine and Cell Therapy Lab.
Blog
Thoughts and research snippets
October 21, 2020We've previously written about the OpenVax neoantigen prediction pipeline, which is the...Cancer immunotherapy aims to recruit the body's own immune system to attack a tumor, which...June 27, 2018 · immunologyUri Laserson organized a delightful class at Mount Sinai called Applications of DNA Sequencing...